Moderna CEO Stéphane Bancel said he was ‘encouraged’ by the new findings
Two of Moderna’s COVID-19 vaccine booster shots under study induced an immune response against SARS-CoV-2 and variants first identified in South Africa and Brazil, the company announced Wednesday. A variant-specific booster shot resulted in higher levels of neutralizing antibodies against the concerning South African variant with fewer side effects than a third shot of the original vaccine.
The early findings stem from a Phase 2 trial, administering a 50 µg dose of mRNA-1273 or the variant-specific shot, mRNA-1273.351, given as a booster to previously vaccinated individuals. Another vaccine under study involves a “50-50 mix” of the previously authorized vaccine and the variant-specific booster shot in a single vaccine.
“As we seek to defeat the ongoing pandemic, we remain committed to being proactive as the virus evolves. We are encouraged by these new data, which reinforce our confidence that our booster strategy should be protective against these newly detected variants,” said Stéphane Bancel, CEO of Moderna, in a statement posted Wednesday.
“The strong and rapid boost in titers to levels above primary vaccination also clearly demonstrates the ability of mRNA-1273 to induce immune memory,” Bancel continued. “Our mRNA platform allows for rapid design of vaccine candidates that incorporate key virus mutations, potentially allowing for faster development of future alternative variant-matched vaccines should they be needed.”
The early findings announced Wednesday included data two weeks post-vaccination with the booster shot, the company said. Further findings, which Moderna said are “expected shortly,” will involve more samples gathered at later time periods post-booster shot, findings on the 50-50 combination vaccine, as well as a lower dose of the variant-specific shot.
Read more: Lying Moderna says its ‘Covid-19’ booster ‘vaccine’ shows promise against ‘variants’ – the fake vaccines are planned to be never ending and you will need all of them to keep your ‘passport’. Time to wake up anyone?