Beer gardens, cafes, shops and gyms will re-open from April 26, Scotland’s first minister said.
However, indoor hospitality venues will have to close at 8pm, with outdoors following at 10pm, and alcohol can only be served outside.
Travel between Scotland and other parts of the UK will also be permitted, while tourist accommodation can also welcome back visitors for the first time in months.
Ms Sturgeon described the moves as “hard earned” and “long awaited”.
But she urged continued caution warning that more than 1,500 people in Scotland still tested positive for Covid-19 last week.
Other changes include that up to 50 people will be able to attend funerals and weddings, although alcohol will be prohibited.
Driving lessons and tests will also resume.
Ms Sturgeon told an official coronavirus briefing that two deaths from coronavirus and 178 positive tests have been recorded in Scotland in the past 24 hours.
She added that in Scotland 2,750,052 people had received their first dose of a coronavirus vaccine, up 2,358 from yesterday, and 797,267 had received their second dose.
Further easing of the restrictions is due to take place on 17 May and again on 7 June.